There's a newer version of Pico CSS!

Containers

.container enable a centered viewport.
.container-fluid enable a 100% layout.

<body>
  <main class="container"></main>
</body>

Pico uses the same breakpoints and viewports sizes as Bootstrap.

DeviceExtra smallSmallMediumLargeExtra large
Breakpoint<576px≥576px≥768px≥992px≥1200px
Viewport100%540px720px960px1140px

<header>, <main> and <footer> as direct children of <body> provide a responsive vertical padding

<section> provides a responsive margin-bottom to separate your sections.